clinical_evidence_briefer
ActiveTool of @gapup/mcp-knowledge
Brief évidence clinique (GRADE) — Gapup agent-payable C-suite expertise (RISK). Returns a structured, audited deliverable. Answers: Review the clinical evidence for <drug/intervention> in <indication> — GRADE rating, key trials, safety signals. · Scan safety signals for <molecule> in <population> — adverse events, severity, frequency from FAERS and trial data. · Assess comparative effectiveness of <intervention> versus <comparator> for <disease> — what does the evidence show? · Is there evidence supporting drug repurposing of <molecule> for <new indication> — existing trials and GRADE quality? · What are the evidence gaps for <intervention> in <patient population> before formulary adoption? Reference case: Semaglutide 2.4mg · Chronic weight management in non-diabetic adults · GRADE high efficacy · studies found · nausea/GI signals · FDA approved · PubMed+ClinicalTrials+OpenFDA. Inputs are validated server-side — send the documented case fields.
Parameters schema
{
"type": "object",
"required": [
"topic",
"max_studies",
"evidence_focus",
"date_range_years"
],
"properties": {
"async": {
"type": "boolean",
"description": "If true, returns a job_id immediately (<200ms) instead of waiting for the result. Poll the result with job_result(job_id). Use for slow tools to avoid client timeouts."
},
"topic": {
"type": "string",
"maxLength": 300,
"minLength": 3
},
"max_studies": {
"type": "integer",
"default": 20,
"maximum": 50,
"minimum": 5
},
"intervention": {
"type": "string",
"maxLength": 200
},
"evidence_focus": {
"enum": [
"efficacy",
"safety",
"adverse-events",
"comparative-effectiveness",
"all"
],
"type": "string",
"default": "all"
},
"target_disease": {
"type": "string",
"maxLength": 200
},
"date_range_years": {
"type": "integer",
"default": 5,
"maximum": 20,
"minimum": 1
},
"intervention_type": {
"enum": [
"drug",
"device",
"biologic",
"procedure",
"behavioral",
"diagnostic"
],
"type": "string"
}
},
"additionalProperties": true
}Parent server
@gapup/mcp-knowledge
https://github.com/getgapup/gapup-mcp
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