string_homology

Active

declared in 2.13.1

Retrieves pairwise protein similarity scores (Smith–Waterman bit scores) for the query proteins. - If no target species (`species_b`) is provided, results are intra-species (within the query species). - To retrieve homologs in other species or clades (e.g. vertebrates, yeast, plants), specify one or more NCBI taxon IDs in `species_b`. - Multiple target species are supported; ask the user to clarify if needed. - Always report species names together with their taxon IDs. - Bit scores < 50 are not reported. - Results are truncated to the top 50 proteins per input protein.

Parameters schema

{
  "type": "object",
  "required": [
    "proteins"
  ],
  "properties": {
    "species": {
      "anyOf": [
        {
          "type": "string",
          "description": "Required. NCBI/STRING taxon (e.g. 9606 for human, or STRG0AXXXXX for uploaded genomes)."
        },
        {
          "type": "null"
        }
      ],
      "default": null
    },
    "proteins": {
      "type": "string",
      "description": "Required. One or more protein identifiers, separated by %0d. Example: SMO%0dTP53"
    },
    "species_b": {
      "anyOf": [
        {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "description": "Optional. One or more NCBI taxon IDs for target species, separated by comma (e.g. 9606,7227,4932 for human, fly, and yeast)."
        },
        {
          "type": "null"
        }
      ],
      "default": null
    }
  }
}

What this tool wraps· 0 endpoints

min confidence0.70 0.50

No endpoints wrapped at confidence ≥ 0.70.

Parent server

STRING Database MCP Server

https://github.com/meringlab/string-mcp

2/7 registries

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