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string_functional_annotation

Active

Tool of STRING Database MCP Server

declared in 2.13.1

This tool retrieves curated functional annotations for a set of proteins. Each input protein is mapped to known biological terms from ontologies, pathway databases, tissues, compartments and domains — such as Gene Ontology (GO), KEGG, and UniProt Keywords. - Use this when the user asks what a protein does, where it's localized, expressed, or which pathways it participates in. - Keep the output short and focused by highlighting a few diverse and specific annotations for each protein. - This tool does not perform statistical enrichment — use the enrichment tool for that. Output fields (per protein): - stringId: STRING protein identifier - preferredName: Gene name or alias - annotation: Functional description or keyword - category: Source category (e.g. GO, KEGG, Keyword) - term: Functional term or ID

Parameters schema

{
  "type": "object",
  "required": [
    "identifiers"
  ],
  "properties": {
    "species": {
      "anyOf": [
        {
          "type": "string",
          "description": "Required. NCBI/STRING taxon (e.g. 9606 for human, or STRG0AXXXXX for uploaded genomes)."
        },
        {
          "type": "null"
        }
      ],
      "default": null
    },
    "identifiers": {
      "type": "string",
      "description": "Separate multiple protein queries by %0d. e.g. SMO%0dTP53"
    },
    "detail_for_term": {
      "anyOf": [
        {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "description": "Optional. Exact functional term ID to return with the full list of matching input proteins. Use this when a previous result says a protein list was shortened, omitted, or replaced with 'many'."
        },
        {
          "type": "null"
        }
      ],
      "default": null
    }
  }
}

What this tool wraps· 1 endpoint

min confidence0.700.50

Parent server

STRING Database MCP Server

https://github.com/meringlab/string-mcp

2/7 registries
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string_functional_annotation — STRING Database MCP Server — PRSM MCP