query

Active

declared in 0.1.0

Search aggregated human genetic-variant annotations on MyVariant.info. Accepts an rsID ("rs58991260"), an HGVS id ("chr1:g.218631822G>A"), or a fielded query ("dbnsfp.genename:CDK2", "clinvar.rcv.clinical_significance:pathogenic"). Each hit merges dbSNP, ClinVar clinical significance, CADD/dbNSFP deleteriousness scores, and gnomAD population allele frequencies. Returns { total, hits }; hit._id is usually the HGVS id you can pass to the variant tool.

Parameters schema

{
  "type": "object",
  "required": [
    "query"
  ],
  "properties": {
    "size": {
      "type": "number",
      "description": "Max hits to return, 1-1000 (default 10)."
    },
    "query": {
      "type": "string",
      "description": "rsID, HGVS id, or fielded query. e.g. \"rs58991260\", \"chr1:g.218631822G>A\", \"dbnsfp.genename:CDK2\"."
    },
    "fields": {
      "type": "string",
      "description": "Comma-separated return fields (default: all). e.g. \"dbsnp,clinvar,cadd.phred,gnomad_genome.af\"."
    }
  }
}

What this tool wraps· 0 endpoints

min confidence0.70 0.50

No endpoints wrapped at confidence ≥ 0.50.

Parent server

mcp-myvariant

https://github.com/pipeworx-io/mcp-myvariant

2/7 registries

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