ortholog_map

Active

declared in 1.1.0

Look up the orthologous (or paralogous) gene for up to 50 gene symbols in a target species, via Ensembl's homology-by-symbol REST endpoint. Symbols with no homology record are reported in `unmapped`, never silently dropped.

Parameters schema

{
  "type": "object",
  "required": [
    "symbols",
    "targetSpecies"
  ],
  "properties": {
    "type": {
      "enum": [
        "orthologues",
        "paralogues",
        "all"
      ],
      "type": "string",
      "default": "orthologues",
      "description": "Homology type to return. Defaults to orthologues."
    },
    "symbols": {
      "type": "array",
      "items": {
        "type": "string"
      },
      "description": "Gene symbols to look up, up to 50 (e.g. [\"TP53\", \"BRCA1\"])."
    },
    "sourceSpecies": {
      "type": "string",
      "default": "human",
      "description": "Ensembl species slug the symbols belong to (e.g. \"human\", \"mouse\"). Defaults to \"human\"."
    },
    "targetSpecies": {
      "type": "string",
      "description": "Ensembl species slug to find homologs in (e.g. \"mouse\", \"rat\", \"zebrafish\", \"fruit_fly\")."
    }
  },
  "additionalProperties": false
}

What this tool wraps· 1 endpoint

min confidence0.70 0.50

Data resourceEnsembl Genome Browser
EMBL-EBI · scientific-data
name mention0.70

Parent server

com.seqbench/workbench

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