vep

Active

declared in 0.1.0

"What's the effect of [variant]" / "predict consequences of [genomic change]" / "VEP for [chrom:pos]" — Variant Effect Predictor for a specified region + allele. Returns consequences (missense, synonymous, splice, etc.), affected genes, transcript impacts, SIFT/PolyPhen predictions. Use for variant interpretation in clinical or research genomics.

Parameters schema

{
  "type": "object",
  "examples": [
    {
      "allele": "C",
      "region": "9:22125504-22125504:1",
      "species": "human"
    }
  ],
  "required": [
    "species",
    "region",
    "allele"
  ],
  "properties": {
    "allele": {
      "type": "string",
      "description": "e.g. \"C\""
    },
    "region": {
      "type": "string",
      "description": "e.g. \"9:22125504-22125504:1\""
    },
    "species": {
      "type": "string"
    }
  }
}

What this tool wraps· 1 endpoint

min confidence0.70 0.50

Data resourceEnsembl Genome Browser
EMBL-EBI · scientific-data
name mention0.85

Parent server

Ensembl

https://github.com/pipeworx-io/mcp-ensembl

1/7 registries

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